Application
LRP1 (85kDa subunit) antibody detects LRP1 (85kDa subunit) protein by western blot analysis. A. 30 μg HeLa whole cell extract 5 % SDS-PAGE LRP1 (85kDa subunit) antibody dilution: 1:1000| Product Name | LRP1 (85kDa subunit) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to LRP1 (85kDa subunit) (low density lipoprotein receptor-related protein 1)The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human LRP1 (85kDa subunit). The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, ChickenMouse (100%), Rat (100%), Chicken (96%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | LRP1A , A2MR , LRP , TGFBR5 , CD91 , APR , APOER , IGFBP3R , low density lipoprotein receptor-related protein 1 , LRP1 |
|---|---|
| Target | LRP1 (85kDa subunit) |
| Molecular Weight(MW) | 505 kDa (note) |
| Cellular Localization | Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein , Membrane , coated pit , Low-density lipoprotein receptor-related protein 1 515 kDa subunit: Cell membrane; Peripheral membrane protein; |
Application
LRP1 (85kDa subunit) antibody detects LRP1 (85kDa subunit) protein by western blot analysis. A. 30 μg HeLa whole cell extract 5 % SDS-PAGE LRP1 (85kDa subunit) antibody dilution: 1:1000| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
