Rabbit Polyclonal antibody to LRRC8AThis gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Immunogen
LRRC8A antibody was raised against a 15 amino acid peptide near the amino terminus of human LRRC8A.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
WB: 1 - 2 ug/ml
Species Reactivity
Mouse
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
leucine rich repeat containing 8 family, member A , AGM5 , LRRC8
Target
LRRC8A
Tissue Specificity
LRRC8A antibody is mouse specific.
Application
Application
Western blot analysis of LRRC8A in EL4 cell lysate with LRRC8A antibody at (A) 1 and (B) 2 ug/ml.
Application Notes
WB: 1 - 2 ug/ml
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year.