Application
WB analysis of HT29 lysates using LXR alpha antibody.Application
IHC-P of Human liver tissue using LXR alpha antibodyApplication
WB analysis of mouse kidney and rat liver, using LXR alpha antibody.| Product Name | LXR alpha antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to LXR alphaThe protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| Immunogen | Recombinant protein of human NR1H3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | RLD-1 , NR1H3 , nuclear receptor subfamily 1, group H, member 3 , LXR-a , LXRA |
|---|---|
| Target | LXR alpha |
| Molecular Weight(MW) | 50 kDa (note) |
Application
WB analysis of HT29 lysates using LXR alpha antibody.
Application
IHC-P of Human liver tissue using LXR alpha antibody
Application
WB analysis of mouse kidney and rat liver, using LXR alpha antibody.| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
