Rabbit Polyclonal to Human Lysozyme ( Muramidase )This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the anti-microbial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. Missense mutations in LYZ have been identified in heritable renal amyloidosis. [provided by RefSeq]
Immunogen
Purified human lysozyme from urine of patients with monocystic leukemia.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHCIHC-FIHC-P
This antibody can be used on formalin-fixed, paraffin-embedded tissue sections. Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:30 to 1:60 with AutoProbe III (GTX28620). Predigestion with proteolytic enzyme (GeneTex cat. # GTX73181/GTX73182) improves staining of formalin fixed paraffin-embedded tissue sections. It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Unpurified
Target Information
Gene Synonyms
4069, 105200, LYZ, Lysozyme, P61626
Target
Lysozyme
Tissue Specificity
Lysozyme hydrolyzes certain glycosidic linkages of polysaccharides found in the cell walls of some bacteria. This enzyme is found in macrophages and in neutrophil granulocytes.
Application
Application
IHC-P analysis of human tonsil using Lysozyme antibody.
Application
IHC Image using - Detection of Lysozyme by IHC in Human Tonsil
Application Notes
This antibody can be used on formalin-fixed, paraffin-embedded tissue sections. Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:30 to 1:60 with AutoProbe III (GTX28620). Predigestion with proteolytic enzyme (GeneTex cat. # GTX73181/GTX73182) improves staining of formalin fixed paraffin-embedded tissue sections. It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.