Rabbit polyclonal antibody to MAK (male germ cell-associated kinase)The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human MAK. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Zebrafish, Xenopus laevis, BovineMouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (94%), Bovine (98%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
dJ417M14.2 antibody, MAK antibody, serine/threonine protein kinase MAK antibody, male germ cell-associated kinase retinal-enriched isoform antibody, serine/threonine-protein kinase MAK antibody, male germ cell-associated kinase antibody
Target
MAK
Molecular Weight(MW)
71 kDa (note) (4)
Application
Application
Sample(30 μg of whole cell lysate) A:Raji 7.5% SDS PAGE diluted at 1:1000
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.