Polyclonal Anti - MAP - 1A novel Bax-associating protein, named MAP-1 (Modulator of Apoptosis), mediates caspase-dependent apoptosis in mammalian cells when overexpressed. MAP-1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-X(L) of the Bcl-2 family in vitro and in vivo in mammalian cells. These data suggest that MAP-1 mediates apoptosis through a mechanism that involves binding to Bax.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Target Information
Gene Synonyms
MAP-1, PNMA4, MAP 1, MAP1
Target
MAP1
Tissue Specificity
Reacts with residues 337-351 of the human MAP-1 protein.
Application
Application
Western blot analysis of human MAP-1 in 293T cells with anti-MAP-1 at a 1:250 dilution
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.