| Product Name | MARCKS (phospho Ser152/Ser156) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to MARCKS (phospho Ser152/Ser156)MARCKS (Myristoylated alanine-rich protein kinase C substrate) is a major PKC substrate that is distributed in various cell types. MARCKS has been implicated in cell motility, cell adhesion, phagocytosis, membrane traffic and mitogenesis. PKC phosphorylates Ser152, 156 and 163 of MARCKS, which regulates MARCKS's calcium/calmodulin binding activity and filamentous (F)-actin cross-linking activity. In addition, phosphorylation by PKC results in translocation of MARCKS from membrane to cytoplasm. |
| Modification | p-Ser152/Ser156 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blotting (1:200-1000). However, the optimal conditions should be determined individually. Other applications have not been determined. The antibody detects 80 kDa MARCKS only when phosphorylated at Ser152/156.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MACS PRKCSL phospho-MARCKS (pSer152/Ser156) phospho MARCKS (pSer152/Ser156) phospho-MARCKS (pS152/S156) phospho MARCKS (pS152 and S156) phosphoMARCKS (pSer152/Ser156) FLJ14368 phosphoMARCKS (pS152/S156) phosphomyristin MRACKS MARCKS phospho MAR |
|---|---|
| Target | MARCKS (phospho Ser152/Ser156) |
| Tissue Specificity | This antibody is specific for MARCKS (phospho Ser152/Ser156). |
| Application Notes | Western blotting (1:200-1000). However, the optimal conditions should be determined individually. Other applications have not been determined. The antibody detects 80 kDa MARCKS only when phosphorylated at Ser152/156.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Store at +4C. Product should remain stable for at least 12 months. |
| Storage Buffer | PBS (pH 7.2) containing 50% glycerol, 1% BSA, 0.02% thimerosal |
