Rabbit polyclonal to MCL1 predilutedInvolved in programing of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it.
Immunogen
Synthetic peptide: SPEEELDGYEPEPLGKRPA, corresponding to amino acids 121-139 of Human MCL1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-P
IHC-P: Ready diluted. For 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanDogCat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
BCL2L3 EAT MCL1-ES MCL1L MCL1S MGC104264 MGC1839 Mcl-1 TM bcl2-L-3 mcl1/EAT Mcl 1 MCL1 ES bcl2 L 3 Mcl1 MCL1ES
Target
MCL1
Cellular Localization
Cell Membrane
Application
Application
Application
Application
staining MCL1 in human tonsil by Immunohistochemistry (FFPE-sections).
Application
Human Tonsil stained with anti-MCL-1 antibody
Positive Control
Tonsil
Application Notes
IHC-P: Ready diluted. For 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution and store at 4°C. Do not freeze.
Storage Buffer
PBS, pH 7.4 containing 1%BSA and 0.1% sodium azide