Application
Confocal immunofluorescence analysis of HepG2 cells using anti-MCL1 mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.Application
Immunohistochemical analysis of paraffin-embedded human lymphnode tissues using anti-MCL1 mAb with DAB staining.Application
Western blot analysis using anti-MCL1 mAb against Hela (1), BCBL-1 (2), Jurkat (3) and HL60 (4) cell lysate.| Product Name | MCL1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [8C6, 8C6D4B1] to MCL-1This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010] |
| Immunogen | The immunogen corresponding to human MCL-1 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 8C6, 8C6D4B1 |
| Host Species | Mouse |
| Tested Applications | ELISAICC/IFIHCIHC-PWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Gene Synonyms | TM MCL1 EAT MCL1S BCL2L3 MCL1/EAT MCL1L BCL2-L-3 MCL1-ES |
|---|---|
| Target | MCL-1 |
| Molecular Weight(MW) | 37 kDa (note) |
| Cellular Localization | Cytoplasmic, associated with mitochondria. |
Application
Confocal immunofluorescence analysis of HepG2 cells using anti-MCL1 mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
Application
Immunohistochemical analysis of paraffin-embedded human lymphnode tissues using anti-MCL1 mAb with DAB staining.
Application
Western blot analysis using anti-MCL1 mAb against Hela (1), BCBL-1 (2), Jurkat (3) and HL60 (4) cell lysate.| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Purified antibody in PBS containing 0.03% sodium azide. |
