Application
IHC-P analysis of human tonsil tissue using MCM2 antibody [CRCT2.1 (D1.9H5)].| Product Name | MCM2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [CRCT2.1] to MCM2The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012] |
| Immunogen | Bacterially expressed human Mcm2. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | CRCT2.1 |
| Host Species | Mouse |
| Tested Applications | IHC-FIHC-PWB |
| Immunohistology - Frozen: 1/500 - 1/1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | minichromosome maintenance complex component 2 CCNL1 MITOTIN CDCL1 D3S3194 BM28 cdc19 |
|---|---|
| Target | MCM2 |
| Tissue Specificity | This antibody recognizes human DNA replication licensing factor MCM2. |
Application
IHC-P analysis of human tonsil tissue using MCM2 antibody [CRCT2.1 (D1.9H5)].| Application Notes | Immunohistology - Frozen: 1/500 - 1/1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide |
