| Product Name | M-CSF Receptor antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [5V36] to CSF1RThe protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant M-CSFR EC domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 5V36 |
| Host Species | Mouse |
| Tested Applications | NeutWB |
| WB(1:500-2000)|Neutralization of M-CSF R bioactivity: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HDLS FIM2 CSF1R C-FMS CSFR CD115 colony stimulating factor 1 receptor CSF-1R FMS M-CSF-R |
|---|---|
| Target | M-CSF R |
| Tissue Specificity | This antibody was selected for its ability to detect human CSF1R. |
| Application Notes | WB(1:500-2000)|Neutralization of M-CSF R bioactivity: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
