Application
IHC analysis of human spleen using MD-1 antibody at 10 µg/ml.Application
Western blot analysis of MD-1 in Ramos lysate using MD-1 antibody at 2 µg/ml.| Product Name | MD1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to MD1Mammalian MD1 is a homolog of Chicken MD1, which was previously isolated as a v-myb-regulated gene, since its transcription increases rapidly after v-myb induction. MD1 is associated at the cell surface with RP105. RP105 is a leucine-rich repaeat (LRR) molecule that is expressed on B-lymphocytes. It was first identified by a mAb that protects spleen B cells from irradiation-induced apoptosis. LRR proteins, such as Toll receptors, have a role in innate immunity. MD1 does not have any homology to other molecules. MD1 when expressed alone behaves as a secretory protein. Expression of MD1 in a cell increasesthe expression of RP105. |
| Immunogen | Synthetic peptide: CGRRKGEQIYYAGP conjugated to KLH, corresponding to amino acids 112-125 of Human MD1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB: Use at a concentration of 2 μg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 33 kDa). Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | MD-1 MMD-1 dJ80N2.1 MD 1 MMD 1 MD1 MMD1 |
|---|---|
| Target | MD1 |
| Cellular Localization | Plasma membrane |
Application
IHC analysis of human spleen using MD-1 antibody at 10 µg/ml.
Application
Western blot analysis of MD-1 in Ramos lysate using MD-1 antibody at 2 µg/ml.| Positive Control | Ramos cell lysate. |
|---|---|
| Application Notes | WB: Use at a concentration of 2 μg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 33 kDa). Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.05% Sodium Azide; Constituents: PBS |
