Application
Immunohistochemistry of MD-1 in human spleen tissue with MD-1 antibody at 2 ug/ml.Application
Western blot analysis of MD-1 in Daudi cell lysate with MD-1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.| Product Name | MD1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to MD1Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway.. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MD-1 Lymphocyte antigen86 MD1 Lymphocyte antigen 86 MD 1 |
|---|---|
| Target | MD1 |
| Tissue Specificity | This antibody is specific for MD1. |
Application
Immunohistochemistry of MD-1 in human spleen tissue with MD-1 antibody at 2 ug/ml.
Application
Western blot analysis of MD-1 in Daudi cell lysate with MD-1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.| Positive Control | Blocking Peptide: Cat.No. GTX85066-PEP - MD-1 Peptide Lysates: Cat. No. GTX23951 - Daudi Cell Lysate |
|---|---|
| Application Notes | IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Antibody is supplied in PBS containing 0.02% sodium azide |
