Rabbit polyclonal antibody to MelanopsinPhotoreceptor required for regulation of circadian rhythm. Contributes to pupillar reflex and other non-image forming responses to light. May be able to isomerize covalently bound all-trans retinal back to 11-cis retinal.
Immunogen
The antiserum was produced against synthesized peptide derived from human Melanopsin.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
ELISA: 1:1000
Optimal dilutions should be determined experimentally by the end user.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
Opsin-4, Opsin4, MOP, OPN4, Melanopsin, Opsin 4
Target
Melanopsin
Molecular Weight(MW)
52 kDa (note)
Tissue Specificity
OPN4 Antibody detects endogenous levels of total Melanopsin protein.
Cellular Localization
Found in soma, dendrites and proximal part of axons of certain retinal ganglion cells.
Application
Application
Western blot analysis of extracts from COLO cells, using OPN4 Antibody. The lane on the right is treated with the synthesized peptide.
Application Notes
ELISA: 1:1000
Optimal dilutions should be determined experimentally by the end user.
Additional Information
Form
Liquid
Storage Instructions
Store at -20 degrees Celcius. Product is stable for at least 1 year.
Storage Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.