Rabbit Polyclonal antibody to MelanopsinMelanopsin is an opsin-like protein found in the retinal ganglion cells of mammals. Melanopsin is believed to be part of a secondary optical system that parallels that of the classic rod and cone system. This second system reports directly to the suprachiasmatic nucleus and is responsible for regulation of circadian rhythms. Melanopsin is believed to be the primary photopigment responsible for the regulation of these circadian rhythms, and Melanopsin knockout mice have been generated which demonstrate decreased capacity to entrain to light and dark cycles.
Immunogen
Synthetic peptide corresponding to residues K M(1) N S P S E S R V P S S L T Q D P S F(19) of rat melanopsin.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ICC/IFIHCWB
ICC/IF: 10 ug/ml
Species Reactivity
MouseRatHamster
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
Opn4, opsin 4
Target
Melanopsin
Application
Application
WB analysis of overexpressed melanopsin in HEK293 cells using Melanopsin antibody.
Application
ICC/IF analysis of rat retinal ganglion cells using Melanopsin antibody.
Application Notes
ICC/IF: 10 ug/ml
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
PBS containing 1 mg/ml BSA and 0.05% sodium azide.