Application
Western Blot: MEL-1B-R Antibody [ - Western blot (WB) analysis of MEL-1B-R (V39) antibody in extracts from 293/Jurkat/HepG2 cells.| Product Name | Melatonin receptor 1B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Melatonin receptor 1BThe melatonin receptors, MEL-1A-R and MEL-1B-R, are members of the superfamily of guanine nucleotide-binding regulatory protein (G protein)-coupled receptors. The melatonin receptors are activated by the hormone melatonin (Mel), which is secreted by the pineal gland at night as part of the circadian clock. MEL-1A-R, a 37 kD protein, is thought to be involved in pacing the biological clock. However, both MEL-1A-R and MEL-1B-R are implicated in controlling cellular growth in response to melatonin. MEL-1B-R is an integral membrane protein expressed in retina and less in brain and hippocampus. Functional studies of NIH/3T3 cells stably expressing the MEL-1B-R melatonin receptor indicate that it is coupled to inhibition of adenylyl cyclase. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| We recommend the following starting dilutions: ELISA 1:1000-1:5000, Western Blot 1:500-1:1000,. Optimal concentration should be determined experimentally by the end user. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | MTNR1A, 4544, melatonin receptor1A, melatonin receptor 1A, melatonin receptor type1A, MEL-1A-R, MT1, MEL1AR, melatonin receptor type 1A, MTNR1B, MEL 1A R |
|---|---|
| Target | Melatonin receptor 1B |
| Tissue Specificity | MEL-1B-R (V39) detects endogenous levels of MEL-1B-R protein. |
Application
Western Blot: MEL-1B-R Antibody [ - Western blot (WB) analysis of MEL-1B-R (V39) antibody in extracts from 293/Jurkat/HepG2 cells.| Application Notes | We recommend the following starting dilutions: ELISA 1:1000-1:5000, Western Blot 1:500-1:1000,. Optimal concentration should be determined experimentally by the end user. |
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| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline, pH 7.2. |
