Rabbit polyclonal antibody to MESP2 (mesoderm posterior 2 homolog (mouse))This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02). [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human mesoderm posterior 2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Reactivity
HumanHuman (100%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
SCDO2 antibody, bHLHc6 antibody, MESP2 antibody, mesoderm posterior protein 2 antibody, class C basic helix-loop-helix protein 6 antibody, mesoderm posterior 2 homolog (mouse) antibody
Target
MESP2
Molecular Weight(MW)
42 kDa (note)
Cellular Localization
Nucleus
Positive Control
Target recombinant protein
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.