Application
Western blot analysis of MettL7A in MCF cell lysate with MettL7A antibody at 2 ug/ml.Application
Immunocytochemistry of MettL7a in MCF7 cells with MettL7a antibody at 2 ug/ml.| Product Name | MettL7A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to MettL7AMettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. At least two isoforms of MettL7A are known to exisit. This antibody is predicted to not cross-react with MettL7B. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFWB |
| ICC/IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MettL7A Methyltransferaselike protein 7A Methyltransferase-like protein 7A Methyltransferaselike protein7A |
|---|---|
| Target | MettL7A |
| Tissue Specificity | This antibody is specific for MettL7A Internal |
Application
Western blot analysis of MettL7A in MCF cell lysate with MettL7A antibody at 2 ug/ml.
Application
Immunocytochemistry of MettL7a in MCF7 cells with MettL7a antibody at 2 ug/ml.| Positive Control | Blocking Peptide: Cat.No. GTX85369-PEP - MettL7A Peptide Lysates: Cat. No. GTX23871 - MCF7 Cell Lysate |
|---|---|
| Application Notes | ICC/IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
