Application
Immunohistochemistry of Mett7LB in human spleen tissue with MettL7B antibody at 2.5 ug/ml.Application
Western blot analysis of MettL7B in rat spleen tissue lysate with MettL7B antibody at (A) 2 and (B) 4 ug/ml.| Product Name | MettL7B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to MettL7BMettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. This MettL7B antibody is predicted to not cross-react with MettL7A. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Methyltransferaselike protein 7B MettL7B Methyltransferase-like protein 7B Methyltransferaselike protein7B |
|---|---|
| Target | MettL7B |
| Tissue Specificity | This antibody is specific for MettL7B C-Terminus |
Application
Immunohistochemistry of Mett7LB in human spleen tissue with MettL7B antibody at 2.5 ug/ml.
Application
Western blot analysis of MettL7B in rat spleen tissue lysate with MettL7B antibody at (A) 2 and (B) 4 ug/ml.| Positive Control | Blocking Peptide: Cat.No. GTX85370-PEP - MettL7B Peptide Lysates: Cat. No. GTX27945 - Rat Spleen Tissue Lysate |
|---|---|
| Application Notes | IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
