Application
mGluR2/3 polyclonal antibody (1:250 dilution) was used on perfusion-fixed tissue from rat spinal cord.Application
Western Blot analysis of rat brain showing bands migrating at ~100 kDa and ~190 kDa (which may be a dimer of the smaller band).| Product Name | mGluR2 + mGluR3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Anti-mGluR2/3 Polyclonal AntibodyMetabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCWB |
| For WB: Use at 1:500 dilution: |
|
| Species Reactivity | Rat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | Metabotropic glutamate receptor |
|---|---|
| Target | mGluR2 + mGluR3 |
| Tissue Specificity | Reacts with residues 860-872 [NGREVVDSTTSSL] of the rat mGlurR2/3 protein. Sequence is 100% conserved between mGluR2 and mGluR3. Predicted react to human and mouse. |
Application
mGluR2/3 polyclonal antibody (1:250 dilution) was used on perfusion-fixed tissue from rat spinal cord.
Application
Western Blot analysis of rat brain showing bands migrating at ~100 kDa and ~190 kDa (which may be a dimer of the smaller band).| Application Notes | For WB: Use at 1:500 dilution: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
