Application
Immunohistochemistry: mGluR2/3 Antibody [ - Immunohistochemistry (IHC) analyzes of mGluR2/3 (N867) antibody in paraffin-embedded human brain tissueApplication
Western Blot: mGluR2/3 Antibody [ - Western blot (WB) analysis of mGluR2/3 (N867) antibody in extracts from mouse brain cells.| Product Name | mGluR2/3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Metabotropic Glutamate receptor 2 / 3The mGluR proteins (metabotropic glutamate receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-2, which may interact with GRASP, acts as a receptor for glutamate. It may also be involved in the regulation of neurotransmission suppression and in synaptogenesis or synaptic stablization. mGluR-3,which may interact with GRASP, acts as a receptor for glutamate. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIHC-PWB |
| We recommend the following starting dilutions: ELISA 1:1000-1:5000, Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200,. Optimal concentration should be determined experimentally by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | Metabotropic Glutamate receptor 2 /3 GRM2 G protein coupled receptor family C group1 m 2912 24415 Metabotropic Glutamate receptor2 /3 291224415 G protein coupled receptor family C group 1 m |
|---|---|
| Target | Metabotropic Glutamate receptor 2 / 3 |
| Tissue Specificity | mGluR2/3 |
Application
Immunohistochemistry: mGluR2/3 Antibody [ - Immunohistochemistry (IHC) analyzes of mGluR2/3 (N867) antibody in paraffin-embedded human brain tissue
Application
Western Blot: mGluR2/3 Antibody [ - Western blot (WB) analysis of mGluR2/3 (N867) antibody in extracts from mouse brain cells.| Application Notes | We recommend the following starting dilutions: ELISA 1:1000-1:5000, Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200,. Optimal concentration should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline, pH 7.2. |
