Rabbit polyclonal to MmGluR3L glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups. Group II receptors include GRM3 and are linked to the inhibition of the cyclic AMP cascade.
Immunogen
Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive)
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFIHC-P
ICC: Use at an assay dependent dilution. IHC-P: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Target
mGluR3
Cellular Localization
Plasma membrane
Positive Control
Brain, Neurons and Glia
Application Notes
ICC: Use at an assay dependent dilution. IHC-P: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.