Application
WB analysis of extracts from various cell lines using mGluR8 antibody.Application
IHC-P analysis of human ovarian cancer using mGluR8 antibody.Application
IHC-P analysis of rat brain tissue using mGluR8 antibody at a dilution of 1:200.Application
IHC-P analysis of mouse lung metastasis tissue using mGluR8 antibody at a dilution of 1:200.| Product Name | mGluR8 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to mGluR8L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthetic peptide of human GRM8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| WB: 1:500 - 1:200. IHC: 1:50 - 1:200: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | GRM8 GLUR8 glutamate receptor metabotropic 8 mGlu8 MGLUR8 GPRC1H |
|---|---|
| Target | mGluR8 |
| Molecular Weight(MW) | 102 kDa (note) |
Application
WB analysis of extracts from various cell lines using mGluR8 antibody.
Application
IHC-P analysis of human ovarian cancer using mGluR8 antibody.
Application
IHC-P analysis of rat brain tissue using mGluR8 antibody at a dilution of 1:200.
Application
IHC-P analysis of mouse lung metastasis tissue using mGluR8 antibody at a dilution of 1:200.| Application Notes | WB: 1:500 - 1:200. IHC: 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
