Application
The GRPRC1H C-term Pab is used in Western blot to detect GRPRC1H in mouse brain tissue lysate.| Product Name | mGluR8 antibody, C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Metabotropic Glutamate Receptor 8 (GRPRC1H) (C-term)L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq] |
| Immunogen | KLH conjugated synthetic peptide between 860~889 amino acids from the C-terminal region of human GRPRC1H. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| ELISA: Use at 1:1,000: |
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| Species Reactivity | HumanMouse |
| Concentration | 0.2mg/ml |
| Purification | Protein G |
| Gene Synonyms | Metabotropic glutamate receptor8 GRM8 MGLUR8 GPRC1H Metabotropic glutamate receptor 8 |
|---|---|
| Target | Metabotropic Glutamate Receptor 8 (GRPRC1H) |
| Molecular Weight(MW) | 101.74 kDa (note) |
Application
The GRPRC1H C-term Pab is used in Western blot to detect GRPRC1H in mouse brain tissue lysate.| Application Notes | ELISA: Use at 1:1,000: |
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| Form | Liquid |
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| Storage Instructions | Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.09% (W/V) sodium azide |
