| Product Name | MIP1 beta antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to MIP1 beta (chemokine (C-C motif) ligand 4)Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MIP1 beta. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Reactivity | HumanHuman (100%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ACT2 antibody AT744.1 antibody G-26 antibody LAG1 antibody MGC104418 antibody MGC126025 antibody MGC126026 antibody MIP-1-beta antibody MIP1B antibody MIP1B1 antibody SCYA2 antibody SCYA4 antibody CCL4 antibody secreted protein G-26 antibody |
|---|---|
| Target | MIP1 beta |
| Molecular Weight(MW) | 10 kDa (note) |
| Cellular Localization | Secreted |
| Positive Control | Synthetic peptide: 1:8,000 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
