Application
Western blot detection of MKK3 protein in RAW cell (1) and RBL transfected with NIK(2).| Product Name | MKK3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to MKK3MKK3 is a protein kinase that phosphorylates the p38 MAPK but not ERK MAPK. Phosphorylation by MKK3 occurs on threonine and tyrosine residues and increases the activity of p38 to stimulate transcription factors ATF2 and Elk-1. MKK3, together with MKK6, serve as upstream regulators of p38 MAPK activation. A structural variant, MKK3b, has been identified that contains 29 more amino acids at its N- terminus. |
| Immunogen | Recombinant protein - full length human MKK3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| For IP and WB: Use at a dilution of 1:1,500 - 1:2,500. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | Dual specificity mitogen activated protein kinase kinase 3 antibody ERK kinase 3 antibody MAP kinase kinase 3 antibody MAP2K 3 antibody MAPK ERK kinase 3 antibody MAPK kinase 3 antibody MAPKK 3 antibody MAPKK3 antibody MEK 3 antibody Mitogen activated pro |
|---|---|
| Target | MKK3 |
Application
Western blot detection of MKK3 protein in RAW cell (1) and RBL transfected with NIK(2).| Application Notes | For IP and WB: Use at a dilution of 1:1,500 - 1:2,500. Optimal dilutions/concentrations should be determined by the researcher.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline, pH 7.2, containing 0.1% sodium azide |
