Application
MKL1 antibody detects MKL1 protein by western blot analysis. A. 30 μg 293T whole cell lysate/extract B. 30 μg whole cell lysate/extract of human MKL1-transfected 293T cells 7.5 % SDS-PAGE MKL1 antibody dilution: 1:1000| Product Name | MKL1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to MKL1 (megakaryoblastic leukemia (translocation) 1)The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human MKL1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | megakaryoblastic leukemia (translocation) 1 BSAC MAL MRTF-A |
|---|---|
| Target | MKL1 |
| Molecular Weight(MW) | 99 kDa (note) (5) |
| Cellular Localization | Nucleus |
Application
MKL1 antibody detects MKL1 protein by western blot analysis. A. 30 μg 293T whole cell lysate/extract B. 30 μg whole cell lysate/extract of human MKL1-transfected 293T cells 7.5 % SDS-PAGE MKL1 antibody dilution: 1:1000| Positive Control | MKL1-transfected 293T |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
