Rabbit Polyclonal antibody to MLLT11The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008]
Immunogen
KLH conjugated synthetic peptide derived from human MLLT11
Conjugation
Agarose
Modification
Acetylated
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
ELISA(1:500-1000):
Species Reactivity
HumanMouseRat
Predicted Reactivity
Bovine, Rabbit, Horse, Pig, Dog
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog Drosophila) translocated to 11 AF1Q RP11-316M1.10
Target
MLLT11
Tissue Specificity
MLLT11
Application
Application
ELISA analysis with 0.2ug/100ul antigen and serially diluted MLLT11 antibody (1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000).
Application Notes
ELISA(1:500-1000):
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and less than 0.09% sodium azide.