Rabbit Polyclonal antibody to MMAB (methylmalonic aciduria (cobalamin deficiency) cblB type)This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human MMAB. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, BovineMouse (90%), Bovine (89%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
ATR antibody MGC20496 antibody cblB antibody cob antibody MMAB antibody aquocob(I)alamin vitamin B12s adenosyltransferase antibody methylmalonic aciduria type B protein antibody ATP:cob(I)alamin adenosyltransferase antibody ATP:corrinoid adenosyltr
Molecular Weight(MW)
27 kDa (note)
Cellular Localization
Mitochondrion
Application
Application
Immunohistochemical analysis of paraffin-embedded human hepatoma, using MMAB antibody at 1:500 dilution.
Application
Sample (30 ug of whole cell lysate) A: HepG2 12% SDS PAGE diluted at 1:1000
Positive Control
HepG2
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.