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MMP1 antibody

Catalog Number:OM263486
OM263486
Discount Price
OM263486-100ul
1~2 Week
100ul
OM263486-50ul
50ul
OM263486-20ul
20ul
1~2 Week
Product Profile
Product Name MMP1 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to MMP1 (matrix metallopeptidase 1 (interstitial collagenase))Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the center region of human MMP1. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity HumanMouse
Predicted Reactivity Pig, Rabbit, BovinePig (91%), Rabbit (89%), Bovine (86%)
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms CLG antibody
CLGN antibody
MMP1 antibody
matrix metalloproteinase 1 antibody
fibroblast collagenase antibody
interstitial collagenase antibody
matrix metalloprotease 1 antibody
matrix metallopeptidase 1 (interstitial collagenase) antibody
Molecular Weight(MW) 54 kDa (note)
Cellular Localization Secreted , extracellular space , extracellular matrix
Application

Application

MMP1 antibody detects MMP1 protein at secreted on human cervical carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human cervical carcinoma. MMP1 antibody dilution: 1:500.

Application

MMP1 antibody detects MMP1 protein at secreted on human endometrial carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human endometrial carcinoma. MMP1 antibody dilution: 1:500.

Application

Immunohistochemical analysis of paraffin-embedded human breast cancer, using MMP1 antibody at 1:250 dilution.

Application

MMP1 antibody detects MMP1 protein at secreted on mouse prostate by immunohistochemical analysis. Sample: Paraffin-embedded mouse prostate. MMP1 antibody dilution: 1:500.

Application

Whole cell extract (30 µg) was separated by 10% SDS-PAGE, and the membrane was blotted with MMP1 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Positive Control Raji , *dermal fibroblast cells
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
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