Rabbit polyclonal antibody to MMP10 (hinge region)Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to the Hinge region of of human MMP10.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-P
Immunohistology - Paraffin: Min Dilution 10 ug/ml Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
SL-2 MMP10 STMY2
Target
MMP-10 (Hinge Region)
Tissue Specificity
This antibody recognizes both the pro and active form of MMP10.
Application
Application
IHC-P analysis of human kidney tissue using MMP10 (hinge region) antibody.
Application Notes
Immunohistology - Paraffin: Min Dilution 10 ug/ml Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.