| Product Name | MMP11 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [SL3.01] to MMP11Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin 3 (MMP 11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP 11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP 11 expression is found more specifically in malignant tumors than in benign ones. |
| Immunogen | Recombinant protein corresponding to active form of human MMP 11. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | SL3.01 |
| Host Species | Mouse |
| Tested Applications | IPWB |
| IP (native): use at a concentration of 2μg / mg (protein A). Western Blotting: use at a concentration of 0.5 - 1.0μg / ml for 2hrs at RT. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects a band of 60kDa (latent), 47kDa(active), which corresponds to the predicted molecular weight of MMP 11.: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Protein G |
| Gene Synonyms | ST3 SL-3 4320 185261 SL3 STMY3 MMP11 P24347 SL 3 |
|---|---|
| Target | MMP11 |
| Cellular Localization | Secreted |
| Light Chain Type | kappa |
| Positive Control | Recombinant MMP 11 protein. |
|---|---|
| Application Notes | IP (native): use at a concentration of 2μg / mg (protein A). Western Blotting: use at a concentration of 0.5 - 1.0μg / ml for 2hrs at RT. Optimal dilutions / concentrations should be determined by the end user. By Western blot, this antibody detects a band of 60kDa (latent), 47kDa(active), which corresponds to the predicted molecular weight of MMP 11.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide |
