Application
MMP17 antibody [N2C2], Internal detects MMP17 protein at cytosol on human gastria carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human gastria carcinoma. MMP17 antibody [N2C2], Internal dilution: 1:1500. Scale bar = 100 μm.Application
Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE diluted at 1:1000Application
Immunofluorescence analysis of methanol-fixed HeLa, using MMP17 antibody at 1:200 dilution.Application
MMP17 antibody [N2C2], Internal detects MMP17 protein at cytosol and membrane on human gastric cancer by immunohistochemical analysis. Sample: Paraffin-embedded gastric cancer. MMP17 antibody [N2C2], Internal dilution: 1:500.| Product Name | MMP17 antibody , Internal |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to MMP17 (matrix metallopeptidase 17 (membrane-inserted))Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human MMP17. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, RatMouse (93%), Rat (93%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MT4-MMP antibody MMP17 antibody MMP-17 antibody MT4MMP antibody matrix metalloproteinase 17 (membrane-inserted) antibody membrane-type matrix metalloproteinase 4 antibody membrane-type-4 matrix metalloproteinase antibody matrix metalloproteinase-17 |
|---|---|
| Molecular Weight(MW) | 67 kDa (note) |
| Cellular Localization | Isoform Long: Cell membrane; Lipid-anchor , GPI-anchor; Extracellular side , Secreted , extracellular space , extracellular matrix |
Application
MMP17 antibody [N2C2], Internal detects MMP17 protein at cytosol on human gastria carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human gastria carcinoma. MMP17 antibody [N2C2], Internal dilution: 1:1500. Scale bar = 100 μm.
Application
Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE diluted at 1:1000
Application
Immunofluorescence analysis of methanol-fixed HeLa, using MMP17 antibody at 1:200 dilution.
Application
MMP17 antibody [N2C2], Internal detects MMP17 protein at cytosol and membrane on human gastric cancer by immunohistochemical analysis. Sample: Paraffin-embedded gastric cancer. MMP17 antibody [N2C2], Internal dilution: 1:500.| Positive Control | HeLa |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
