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MMP24 antibody

Catalog Number:OM263580
OM263580
Discount Price
OM263580-100ul
1~2 Week
100ul
OM263580-50ul
50ul
OM263580-20ul
20ul
1~2 Week
Product Profile
Product Name MMP24 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to MMP24 (matrix metallopeptidase 24 (membrane-inserted))Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human MMP24. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity HumanMouse
Predicted Reactivity RatRat (83%)
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms matrix metallopeptidase 24 (membrane-inserted)
MT5MMP
MMP25
MTMMP5
MT5-MMP
MT-MMP 5
MMP-24
MT-MMP5
Target MMP24
Cellular Localization Cell membrane; Single-pass type I membrane protein; Extracellular side , Processed matrix metalloproteinase-24: Secreted , extracellular space , extracellular matrix (By similarity)
Application

Application

MMP24 antibody detects MMP24 protein by Western blot analysis. A. 30 µg 293T whole cell lysate/extract B. 30 µg whole cell lysate/extract of human MMP24-transfected 293T cells 7.5 % SDS-PAGE MMP24 antibody dilution: 1:5000

Application

MMP24 antibody detects MMP24 protein by western blot analysis. A. 30 µg SK-N-SH whole cell lysate/extract B. 30 µg IMR32 whole cell lysate/extract 7.5 % SDS-PAGE MMP24 antibody dilution: 1:1000

Application

MMP24 antibody detects MMP24 protein by Western blot analysis. A. 50 µg mouse brain lysate/extract 7.5 % SDS-PAGE MMP24 antibody dilution: 1:1000
Positive Control SK-N-SH , IMR32 , human MMP24-transfected 293T , mouse brain
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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