Application
Immunohistochemical analysis of human salivary gland cancer, using MMP3 antibody at 1:100 dilution.Application
Immunofluorescence analysis of paraformaldehyde-fixed A549, using MMP3 antibody at 1:200 dilution.| Product Name | MMP3 antibody , N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to MMP3 (matrix metallopeptidase 3 (stromelysin 1, progelatinase))Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human MMP3. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-P |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CHDS6 antibody MGC126102 antibody MGC126103 antibody MGC126104 antibody MMP-3 antibody SL-1 antibody STMY antibody STMY1 antibody STR1 antibody MMP3 antibody matrix metalloproteinase-3 antibody transin-1 antibody matrix metalloproteinase 3 (str |
|---|---|
| Molecular Weight(MW) | 54 kDa (note) |
| Cellular Localization | Secreted , extracellular space , extracellular matrix |
Application
Immunohistochemical analysis of human salivary gland cancer, using MMP3 antibody at 1:100 dilution.
Application
Immunofluorescence analysis of paraformaldehyde-fixed A549, using MMP3 antibody at 1:200 dilution.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
