Rabbit polyclonal antibody to MNT (MAX binding protein)The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human MNT. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, BovineMouse (93%), Rat (94%), Bovine (95%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
MAD6 antibody MXD6 antibody ROX antibody bHLHd3 antibody MNT antibody Max-interacting protein antibody myc antagonist MNT antibody max-binding protein MNT antibody class D basic helix-loop-helix protein 3 antibody MAX binding protein antibody
Target
MNT
Molecular Weight(MW)
62 kDa (note)
Cellular Localization
Nucleus
Application
Application
Sample (30 ug of whole cell lysate) A: A431 B: HeLa 7.5% SDS PAGE diluted at 1:1000