Application
MRP3 antibody detects MRP3 protein by western blot analysis. HCT116 whole cell extracts and membrane extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with MRP3 antibody diluted at 1:500.| Product Name | MRP3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to MRP3The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human MRP3. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | EST90757 , ABCC3 , ABC31 , MOAT-D , MLP2 , ATP-binding cassette, sub-family C (CFTR/MRP), member 3 , cMOAT2 |
|---|---|
| Target | MRP3 |
| Molecular Weight(MW) | 169 kDa (note) |
| Cellular Localization | Membrane; Multi-pass membrane protein |
Application
MRP3 antibody detects MRP3 protein by western blot analysis. HCT116 whole cell extracts and membrane extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with MRP3 antibody diluted at 1:500.| Positive Control | HCT116 whole cell extract (unboild) , HCT116 membrane fraction extract (unboild) |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
