Rabbit polyclonal antibody to MRP4The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human ABCC4
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MOAT-B , ATP-binding cassette, sub-family C (CFTR/MRP), member 4 , ABCC4 , MOATB , EST170205
Target
MRP4
Molecular Weight(MW)
97 kDa (note)
Application
Application
IHC-P analysis of human esophageal cancer using MRP4 antibody at a dilution of 1:200.
Application
IHC-P analysis of human esophagus using MRP4 antibody at a dilution of 1:200.
Application Notes
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200.
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.