Rabbit Polyclonal antibody to MRP4The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN2, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq]
Immunogen
KLH conjugated synthetic peptide between 1124~1153 amino acids from the C-terminal region of human ABCC4.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
ELISA: Use at 1:1,000
Species Reactivity
Human
Concentration
0.2mg/ml
Purification
Unpurified
Target Information
Gene Synonyms
MOATB, ATPbinding cassette subfamily C member4, MRP/cMOAT-related ABC transporter, ATPbinding cassette subfamily C member 4, Multidrug resistance, MRP/cMOATrelated ABC transporter, ABCC4, Multispecific organic anion transporter B, ATP-binding cassette sub-
Target
MRP4
Molecular Weight(MW)
149.527 kDa (note)
Application
Application
Western blot analysis of anti-ABCC4 Antibody (C-term) in CEM cell line lysates (35ug/lane). ABCC4 (arrow) was detected using the purified Pab.
Application Notes
ELISA: Use at 1:1,000
Additional Information
Form
Liquid
Storage Instructions
Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.