Rabbit polyclonal antibody to MRPL45Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q. [provided by RefSeq, Jul 2008]
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-245 amino acids from the C-terminal region of human MRPL45.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB : 1:1000
Species Reactivity
Human
Predicted Reactivity
166
Concentration
0.5mg/ml
Purification
Protein A
Target Information
Gene Synonyms
mitochondrial ribosomal protein L45 MRP-L45 L45mt
Target
MRPL45
Application
Application
WB analysis of SK-BR-3 cell lysate (35ug) using MRPL45 antibody.
Application Notes
WB : 1:1000
Additional Information
Form
Liquid
Storage Instructions
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide