Application
Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using MRPS18A Antibody. The picture on the right is treated with the synthesized peptide.| Product Name | MRPS18A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to MRPS18AMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. A pseudogene corresponding to this gene is found on chromosome 3p. Alternative splicing results in multiple transcript variants.[provided by RefSeq] |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MRPS18A. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIHC-P |
| ELISA: 1:40000Optimal dilutions should be determined experimentally by the end user.: |
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MRPS18A MRP-S18-a mitochondrial MRPS183 28S ribosomal protein S18a MRP-S18-3 MRP S18 a MRP S18 3 |
|---|---|
| Target | MRPS18A |
| Molecular Weight(MW) | 22 kDa (note) |
| Tissue Specificity | MRPS18A Antibody detects endogenous levels of total MRPS18A protein. |
Application
Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using MRPS18A Antibody. The picture on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:40000Optimal dilutions should be determined experimentally by the end user.: |
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| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
