Application
ApplicationApplication
Immunohistochemical staining using MSH2 antibody on formalin fixed, paraffin embedded human tonsil tissue.| Product Name | MSH2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [2MSH01] to MSH2MSH2 is involved in DNA repair as a mismatch repair protein, and mutations of MSH2 are found in approximately 50% of inherited non polyposis colorectal carcinoma (HNPCC) (Lynch syndrome) cases. HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. |
| Immunogen | Recombinant MSH2 protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 2MSH01 |
| Host Species | Mouse |
| Tested Applications | IHCIHC-P |
| For IHC-P: Use at a dilution of 1:25. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HNPCC P43246 114030 FCC1 MSH2 4436 COCA1 HNPCC1 |
|---|---|
| Target | MSH2 |
Application
Application
Application
Immunohistochemical staining using MSH2 antibody on formalin fixed, paraffin embedded human tonsil tissue.| Positive Control | Human tonsil tissue |
|---|---|
| Application Notes | For IHC-P: Use at a dilution of 1:25. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Tissue culture supernatant containing 15mM sodium azide |
