Application
MTA1 antibody [C1C3] detects MTA1 protein at nucleus on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. MTA1 antibody [C1C3] dilution: 1:500.Application
MTA1 antibody [C1C3] detects MTA1 protein at nucleus on mouse ovary by immunohistochemical analysis. Sample: Paraffin-embedded mouse ovary. MTA1 antibody [C1C3] dilution: 1:500.Application
MTA1 antibody [C1C3] detects MTA1 protein at nucleus on rat hind brain by immunohistochemical analysis. Sample: Paraffin-embedded rat hind brain. MTA1 antibody [C1C3] dilution: 1:500.Application
MTA1 antibody [C1C3] detects MTA1 protein at nucleus by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: MTA1 protein stained by MTA1 antibody [C1C3] diluted at 1:500. Blue: Hoechst 33342 staining.| Product Name | MTA1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to MTA1 (metastasis associated 1)This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human MTA1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-P |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | MTA1 antibody metastasis-associated protein MTA1 antibody metastasis associated gene 1 protein antibody metastasis associated 1 antibody |
|---|---|
| Molecular Weight(MW) | 81 kDa (note) |
| Cellular Localization | Isoform Short: Cytoplasm , Isoform Long: Nucleus |
Application
MTA1 antibody [C1C3] detects MTA1 protein at nucleus on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. MTA1 antibody [C1C3] dilution: 1:500.
Application
MTA1 antibody [C1C3] detects MTA1 protein at nucleus on mouse ovary by immunohistochemical analysis. Sample: Paraffin-embedded mouse ovary. MTA1 antibody [C1C3] dilution: 1:500.
Application
MTA1 antibody [C1C3] detects MTA1 protein at nucleus on rat hind brain by immunohistochemical analysis. Sample: Paraffin-embedded rat hind brain. MTA1 antibody [C1C3] dilution: 1:500.
Application
MTA1 antibody [C1C3] detects MTA1 protein at nucleus by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: MTA1 protein stained by MTA1 antibody [C1C3] diluted at 1:500. Blue: Hoechst 33342 staining.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
