Rabbit polyclonal antibody to MTMR2 (myotubularin related protein 2)This gene is a member of the myotubularin family. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human MTMR2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Chicken, Rhesus Monkey, BovineMouse (98%), Rat (96%), Chicken (95%), Rhesus Monkey (99%), Bovine (98%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
CMT4B antibody CMT4B1 antibody KIAA1073 antibody MTMR2 antibody myotubularin-related protein 2 antibody myotubularin related protein 2 antibody
Target
MTMR2
Molecular Weight(MW)
73 kDa (note) (4)
Cellular Localization
Cytoplasm , Membrane; Peripheral membrane protein
Application
Application
Sample (30 ug of whole cell lysate) A: U87-MG 7.5% SDS PAGE diluted at 1:1000
Positive Control
NT2D1 , U87-MG
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.