Application
Western blot analysis of Mu Opioid Receptor (pS375) expression in HeLa (A); Raw264.7 (B); rat brain (C) whole cell lysates.| Product Name | Mu Opioid receptor (phospho Ser375) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Mu Opioid receptor (phospho Ser375)This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Mu Opioid Receptor. The exact sequence is proprietary. |
| Modification | p-Ser375 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | OPRM MOR1 MOP OPRM1 opioid receptor mu 1 LMOR M-OR-1 MOR |
|---|---|
| Target | Mu Opioid receptor (phospho Ser375) |
| Tissue Specificity | Recognizes endogenous levels of Mu Opioid Receptor (pS375) protein. |
Application
Western blot analysis of Mu Opioid Receptor (pS375) expression in HeLa (A); Raw264.7 (B); rat brain (C) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
