| Product Name | Anti-Phospho-OPRM1 (Ser375)[Ser377] antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser375/Ser377 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | OPRM1 |
|---|---|
| Gene Synonyms | MOP MOR LMOR MOR1 OPRM M-OR-1 |
| Gene Full Name | opioid receptor mu 1 |
| Gene Summary | This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013] |
| Alternative Names | hMOP LMOR M-OR-1 MOP MOR MOR-1 MOR1 Mu opiate receptor Mu opioid receptor Mu-type opioid receptor Opioid receptor mu 1 OPRM OPRM_HUMAN OPRM1 |
| Molecular Weight(MW) | 45 kDa |
| Cellular Localization | Cell membrane, Cell projection, axon, Perikaryon, Cell projection, dendrite, Endosome, Cytoplasm. |
| SwissProt ID | P35372 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
