Application
Sample (30 ug of whole cell lysate) A: A431 5% SDS PAGE diluted at 1:1000Application
Sample (50 ug of whole cell lysate) A: mouse lung 5% SDS PAGE diluted at 1:500| Product Name | Munc 13-4 antibody , N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Munc 13-4 (unc-13 homolog D (C. elegans))This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human Munc 13-4. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
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| Species Reactivity | HumanMouse |
| Predicted Reactivity | Rat, BovineRat (91%), Bovine (86%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | FHL3 antibody HLH3 antibody HPLH3 antibody Munc13-4 antibody UNC13D antibody protein unc-13 homolog D antibody unc-13 homolog D (C. elegans) antibody |
|---|---|
| Molecular Weight(MW) | 123 kDa (note) (2) |
| Cellular Localization | Cytoplasm , Membrane; Peripheral membrane protein |
Application
Sample (30 ug of whole cell lysate) A: A431 5% SDS PAGE diluted at 1:1000
Application
Sample (50 ug of whole cell lysate) A: mouse lung 5% SDS PAGE diluted at 1:500| Positive Control | A431 , mouse lung |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
