Rabbit Polyclonal antibody to MYBPC1This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Immunogen
MYBPC1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human MYBPC1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAICC/IFWB
WB: 1 ug/ml. IF: 20 ug/ml:
Species Reactivity
MouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
LCCS4 MYBPCC MYBPCS myosin binding protein C slow type
Target
MYBPC1
Tissue Specificity
At least five isoforms of MYBPC1 are known to exist. MYBPC1 antibody is predicted not to cross-react with other MYBPC family members
Application
Application
Western blot analysis of MYBPC1 in rat skeletal muscle tissue lysate with MYBPC1 antibody at 1 ug/mL.
Application
Immunofluorescence of MYBPC1 in mouse skeletal muscle cells with MYBPC1 antibody at 20 ug/mL.
Application Notes
WB: 1 ug/ml. IF: 20 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
MYBPC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
MYBPC1 Antibody is supplied in PBS containing 0.02% sodium azide.