Rabbit polyclonal antibody to MyocilinMYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq, Jul 2008]
Immunogen
Amino acids 69-85 of human Myocilin
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-P
Myocilin antibody can be used in ELISA starting at 1:2000-1:10000, Western Blot starting at 1:200-1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence.:
IHC analysis of retina tissue using Myocilin antibody.
Application Notes
Myocilin antibody can be used in ELISA starting at 1:2000-1:10000, Western Blot starting at 1:200-1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence.:
Additional Information
Form
Liquid
Storage Instructions
This antibody should be stored long term (months) a t-20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.