MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Immunogen
Myocilin antibody was raised against amino acids 69 - 85 of Myocilin (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHC
Myocilin antibody can be used in ELISA starting at 1:2000 - 1:10000, Western Blot starting at 1:200 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence.
Immunohistochemistry staining of Myocilin in eye, retina tissue using Myocilin Antibody.
Application Notes
Myocilin antibody can be used in ELISA starting at 1:2000 - 1:10000, Western Blot starting at 1:200 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence.
Additional Information
Form
Liquid
Storage Instructions
Myocilin antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.